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Handbook of Therapeutic Biomarkers in Cancer

Edited by Sherry X. Yang, Janet E. Dancey

To Be Published December 31st 2012 by Pan Stanford Publishing – 450 pages

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  • Hardback: 9789814364652: $179.95
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  • eBook: 9789814364669:
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Description

This book provides an in-depth description of the biomarkers across a broad area of cancer research and oncology with a wealth of information to specific therapies by a team of internationally recognized experts. The focus of each chapter is on a class of targeted and chemotherapy agents, established and evolving diagnostic tests for therapeutic biomarkers that predict benefit, response, resistance or drug side effects from specific therapeutic interventions. The book serves as a handbook for use by health professionals and scientists on current applicable biomarkers in oncology.

Contents

Overview: Therapeutic Biomarkers in Cancer, Sherry X. Yang and Janet E. Dancey

Statistical Considerations in the Development and Evaluation of Therapeutic Biomarkers in Cancer, Lisa M. McShane, Edward L. Korn and Boris Freidlin

Role of Biomarkers in Clinical Development of New Cancer Therapies, Helen X. Chen

HER2 as a Prognostic and Predictive Biomarker in Cancer, Suparna Wedam and Stan Lipkowitz

Hormone Receptors and Endocrine Therapy in Breast Cancer, Chia C. Portera and Sherry X. Yang

Predictive Biomarkers for Epidermal Growth Factor Receptor (EGFR) Agents in Non-Small Cell Lung Cancer, John Hilton, Penelope A. Bradbury, and Janet E. Dancey

Markers of Sensitivity and Resistance to EGFR Inhibitors in Colorectal Cancer, Jose G. Monzon and Janet E. Dancey

Targeting BCR-ABL for Molecular Therapy of Chronic Myelogenous Leukemia, Shamudheen Rafiyath, Guoqing Wei, and Delong Liu

Gastrointestinal Stromal Tumors (GISTs): From Molecular Pathogenesis to Therapy, Joaquina Baranda, Rashna Madan and Andrew K. Godwin

PML/RARa Fusion Gene and Response to Retinoic Acid and Arsenic Trioxide Treatment, Alicja Gruszka and Myriam Alcalay

Dihydropyrimidine Dehydrogenase Deficiency and 5-Fluouracil Toxicity, Eva Gross and André B. P. van Kuilenburg

UGT1A1 Polymorphisms and Mutations Lead to Irinotecan-Induced Toxicity, Kellie Reece and William D. Figg

The 21-Gene Recurrence Score and Benefit of Chemotherapy in Estrogen Receptor-Positive Breast Cancer, Petra Rietchel and Joseph A. Sparano

MammaPrint for Individualized Recurrence Risk Assessment and Treatment Recommendations for Early-Stage Breast Cancer Patients, Sonal J. Desai and Tianhong Li

BRCA mutation and PARP Inhibitors, Marcie K. Weil, Shivaani Kummar, James H. Doroshow, and Alice P. Chen

EML4-ALK Fusion Gene and Therapy with ALK-targeted Agents in Non-Small Cell Lung Cancer, Vimal Patel, MD and Biren Saraiya

BRAF-Targeted Therapy in Metastatic Melanoma, Noori Kim and April C. Deng

Name: Handbook of Therapeutic Biomarkers in Cancer (Hardback) – Pan Stanford Publishing 
Description: Edited by Sherry X. Yang, Janet E. Dancey. This book provides an in-depth description of the biomarkers across a broad area of cancer research and oncology with a wealth of information to specific therapies by a team of internationally recognized experts. The focus of each chapter is on a class...
Categories: Pathology, Cell Biology, Oncology