Peptide Nucleic Acids

Description

Peptide Nucleic Acids, Second Edition has been extensively revised, updated, and enlarged to contain many new chapters covering the most recent topics and applications in this fast-moving field. The book contains state-of-the-art protocols and applications on all aspects of peptide nucleic acids. Concepts are clearly explained with each chapter containing concise background information. Written by leading experts in the field, the book is an invaluable and complete reference work on this novel and exciting area.

Contents

1. An Introduction to PNA. 2. PNA Synthesis by Boc Chemistry, T. Koch 3. Synthesis of PNA Oligomers by Fmoc Chemistry, R. Casale. 4. Thermodynamics of PNA Interactions. 5. Peptide Nucleic Acid Targeting of Double-Stranded DNA. 6. PNA Beacons and Fluoroprobes. 7. Vector Tagging Via PNA. 8. PCR Clamping. 9. PNA Directed Genome Rare Cutting: New Developments. 10. PNA Openers for Duplex DNA: Basic Facts, Fine Tuning and Emerging Applications. 11. Combined Use of PNA and DNA for Fluorescence In Situ Hybridization (FISH). 12. Production of PNA-Arrays for Nucleic Acid Detection. 13. PNA Antisense in Eukaryotic Systems. 14. Antisense Effects in Escherichia coli.

Related Subjects

1. Genetics
2. Molecular Biology
3. Biotechnology
4. Microbiology