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Description

When looking for a book on fish toxicology, you might find one that discusses the biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You can find resources that cover human and animal toxicology or ecotoxicology in general, but no up-to-date, comprehensive monograph devoted to the effects of chemical pollution on these organisms has been widely available, until now. Filling this void, The Toxicology of Fishes, written by recognized experts, covers toxic responses ranging from reduced reproduction and/or abnormal development, growth, and differentiation.

General Principles — Discusses fundamental topics such as the bioavailability of chemicals present in the aquatic environment to fishes, processes governing chemical distribution within these organisms, how fish metabolize organic chemicals, and fundamental mechanisms of chemical toxicity

Key Target Systems and Organismal Effects — Describes key target organ systems for chemical impacts in fish, how chemicals produce cancer in these animals, and how fishes can develop resistance to chemical toxicity

Methodologies and Applications — Dovers methods for the assessment of chemical effects on fish such as toxicity tests, biomarkers, simulated ecosystems, and modeling approaches and the use of data from such studies in ecological risk assessments

Case Studies — Provides examples of how the principles and approaches presented in earlier units are actually deployed in studies

Illustrated by case studies of actual, large-scale field investigations, the book reviews the tools used to assess unwanted effects in laboratory model- and wild fish in detail. With 238 illustrations, 70 tables, and 50 equations, this comprehensive monograph presents detailed information on the boiavailability of chemical pollutants, their distribution, metabolism, and excretion in the host fish and mechanisms and sites of toxic responses.

Reviews

"… provides a useful resource for the regulatory toxicologist… well-presented and concise book worthy of a position on the bookshelf of all fish toxicologists…."

—Jonathan Burke, Covance Laboratories Ltd, UK, in the British Toxicology Society Newsletter

Contents

General Principles

Introduction, R.T. Di Giulio and D.E. Hinton

Bioavailability of Chemical Contaminants in Aquatic Systems, R.J. Erickson, J.W. Nichols, P.M. Cook, and G.T. Ankley

Toxicokinetics in Fishes, K.M. Kleinow, J.W. Nichols, W.L. Hayton, J.M. McKim, and M.G. Barron

Biotransformation in Fishes, D. Schlenk, M. Celander, E.P. Gallagher, S. George, M. James, S.W. Kullman, P. van den Hurk, and K. Willett

Receptor-Mediated Mechanisms of Toxicity, M.E. Hahn and E.V. Hestermann

Reactive Oxygen Species and Oxidative Stress, R.T. Di Giulio and J.N. Meyer

Key Target Systems and Organismal Effects

Liver Toxicity, D.E. Hinton, H. Segner, D.W.T. Au, S.W. Kullman, and R.C. Hardman

The Osmoregulatory System, S.E. Wendelaar Bonga and R.A.C. Lock

Toxic Responses of the Fish Nervous System, S.P. Bradbury, R.W. Carlson, T.R. Henry, S. Padilla, and J. Cowden

The Endocrine System, P. Thomas

The Immune System of Fish: A Target Organ of Toxicity, E. Carlson and J.T. Zelikoff

Chemical Carcinogenesis in Fishes, J.M. Rotchell, M.R. Miller, D.E. Hinton, R.T. Di Giulio, and G.K. Ostrander

Toxicity Resistance, P.A. Van Veld and D.E. Nacci

Methodologies and Applications

Exposure Assessment and Modeling in the Aquatic Environment, D. Mackay and L. Milford

Fish Toxicity Studies, G.M. Rand

Biomarkers, D. Schlenk, R. Handy, S. Steinert, M.H. Depledge, and W. Benson

Aquatic Ecosystems for Ecotoxicological Research: Considerations in Design Analysis for Fish, T.W. La Point, J.H. Kennedy, J.K. Stanley, and P. Balci

Ecological Risk Assessment, D.R. Mount and T.R. Henry

Case Studies

Mining Impacts on Fish in the Clark Fork River, Montana: A Field Ecotoxicology Case Study, S.N. Luoma, J.N. Moore, A. Farag, T.H. Hillman, D.J. Cain, and M. Hornberger

Toxicology of Synthetic Pyrethroid Insecticides in Fish: A Case Study, J.R. Coats

Reproductive Impairment of Great Lakes Lake Trout by Dioxin-Like Chemicals, D.E. Tillitt, P.M. Cook, J.P. Giesy, W. Heideman, and R.E. Peterson

The Effects of Polycyclic Aromatic Hydrocarbons in Fish from Puget Sound, Washington, L.L. Johnson, M.R. Arkoosh, C.F. Bravo, T.K. Collier, M.M. Krahn, J.P. Meador, M.S. Myers, W.L. Reichert, and J.E. Stein

Effects of the Exxon Valdez Oil Spill on Pacific Herring in Prince William Sound, Alaska, G.D. Marty

Case Study: Pulp and Paper Mill Impacts, M.G. Dubé, K.R. Munkittrick, and L.M. Hewitt

Estrogenic Effects of Treated Sewage Effluent on Fish: Steroids and Surfactants in English Rivers, C.R. Tyler, E.J. Routledge, and R. van Aerle

Index

Name: The Toxicology of Fishes (Hardback)CRC Press 
Description: Edited by Richard T. Di Giulio, David E. HintonContributors: Samuel N. Luoma, Donald Mackay, John J. Stegeman, Peter A. Van Veld, Gary K. Ostrander, Sjoerd Wendela Bonga, Judith T. Zelikoff, Thomas W. La Point, Kevin Kleinow, Mark E. Hahn, Richard E. Peterson, Donald E. Tillitt, Peter Thomas, Gary M. Rand, Kelly R. Munkittrick, Diane E. Nacci, Monique Dube, Joel Robert Coats, Erik A. Carlson, Daniel Schlenk, Lyndal L. Johnson, Gerald Ankley, Steven P. Bradbury, Philip M. Cook, Tala R. Henry, Eli V. Hestermann, Robert A.C. Lock, Gary D. Marty, Joel N. Meyer, David Mount, Charles Tyler, Jeanette Rotchelle, John P. Giesy, John E. Stein, James H. Kennedy, Margaret O. James, Stephen G. George, Mark S. Myers, James M. McKim, John W. Nichols, William L. Hayton, Michael R. Miller, Russell Erickson, Mace G. Barron, William H. Benson, Pinar Balci, Jacob Stanley, Mary Arkoosh, Helmut Segner, Daniel J. Cain, Richard W Carlson, Tracy Collier, Michael H. Depledge, Aida Farag, Evan P. Gallagher, Richard Handy, Michelle Hornberger, Tracy H. Hilman, Maragret Krahn, Seth W. Kullman, James Meador, Lynne Milford, Johnnie Moore, William Reichert, Edwin J. Routledge, Ronny Van Aerle, Scott Steinert, Malin Celander, Peter van den Hurk, Kristine Willett, Doris W.T. Au, Claudia F. Bravo, John Cowden, Ron C. Hardman, Warren Heideman, Stephanie Padilla. When looking for a book on fish toxicology, you might find one that discusses the biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You can find resources that cover human and animal toxicology or ecotoxicology in...
Categories: Marine & Aquatic Science, Environmental & Ecological Toxicology, Zoology